TY - CHAP M1 - Book, Section TI - Chapter 62. Diaphragmatic Pacing A1 - Dimarco, Anthony F. A2 - Tobin, Martin J. PY - 2013 T2 - Principles and Practice of Mechanical Ventilation, 3e AB - Chronic respiratory failure requiring ventilatory support is usually caused by severe derangements in the function of the lungs, chest wall, and/or respiratory muscles. Mechanical ventilation is the only feasible option for most patients with these disorders. In certain patients, however, the function of the respiratory apparatus is completely intact except for lack of adequate nervous output from the respiratory centers in the medulla (central hypoventilation syndrome [CHS])1–3 or interruption of electrical signals from the medulla to the respiratory motoneurons in the spinal cord, which innervate the major inspiratory muscles (cervical spinal cord injury). These patients can be offered an alternative means of respiratory support by diaphragmatic pacing (DP), a more natural and physiologic form of breathing.3–12 SN - PB - The McGraw-Hill Companies CY - New York, NY Y2 - 2024/03/29 UR - accessmedicine.mhmedical.com/content.aspx?aid=57080733 ER -