TY - CHAP M1 - Book, Section TI - Chapter 198. Cutaneous Manifestations of Human Immunodeficiency Virus Disease A1 - Uihlein, Lily Changchien A1 - Saavedra, Arturo P. A1 - Johnson, Richard Allen A2 - Goldsmith, Lowell A. A2 - Katz, Stephen I. A2 - Gilchrest, Barbara A. A2 - Paller, Amy S. A2 - Leffell, David J. A2 - Wolff, Klaus PY - 2012 T2 - Fitzpatrick's Dermatology in General Medicine, 8e AB - |PrintHuman Immunodeficiency Virus (HIV) Infection and Acquired Immune-Deficiency Syndrome (AIDS) at a GlanceAs of 2008, more than 30 million people were living with HIV infection/AIDS.HIV-1 and HIV-2 are human lymphotropic retroviruses that principally infect CD4+ T lymphocytes and CD4+ cells of monocytic lineage.An individual is deemed to have AIDS if he or she is HIV-seropositive with a CD4+ T cell count <200/μL, a CD4+ T cell percentage <14, or any of several diseases deemed to be indicative of a severe defect in cell-mediated immunity.The broad and diverse spectrum of dermatologic disease in HIV infection/AIDS includes inflammatory, infectious, neoplastic, and medication-related disorders.Specific stages of HIV disease (acute HIV syndrome, immune reconstitution, clinically latent disease, and advanced disease) tend to be associated with different dermatologic disorders.Dermatologic disease may help to estimate the level of immunosuppression in HIV infection/AIDS, particularly in resource-limited settings.As there are many dermatologic disorders that are seen in HIV infection/AIDS, this chapter focuses on those diseases that are the most closely associated. SN - PB - The McGraw-Hill Companies CY - New York, NY Y2 - 2024/03/29 UR - accessmedicine.mhmedical.com/content.aspx?aid=56089773 ER -