TY - CHAP M1 - Book, Section TI - Chapter 125. Malignant Fibrous, Fibrohistiocytic, and Histiocytic Tumors of the Dermis A1 - Becker, Jürgen C. A1 - Liegl-Atzwanger, Bernadette A1 - Ugurel, Selma A2 - Goldsmith, Lowell A. A2 - Katz, Stephen I. A2 - Gilchrest, Barbara A. A2 - Paller, Amy S. A2 - Leffell, David J. A2 - Wolff, Klaus PY - 2012 T2 - Fitzpatrick's Dermatology in General Medicine, 8e AB - |PrintMalignant Fibrous Dermal Tumors at a GlanceA group of uncommon and rare cutaneous tumors with varying degrees of malignant potential.Includes dermatofibrosarcoma protuberans (DFSP), atypical fibroxanthoma (AFX), desmoids tumor, myxofibrosarcoma (MFS), undifferentiated pleomorphic sarcomas (UPS), and epithelioid sarcoma (ES).Diagnosis is made by biopsy.DFSP is a locally aggressive tumor with a high rate of local recurrence with rare metastases.AFX is an intermediate-grade neoplasm that usually arises on sun-damaged skin in the eighth decade.Desmoid tumors are slowly growing tumors arising from the muscular aponeurosis that have been associated with a history of trauma or an operation; thus, women undergoing cesarean sections are at greater risk.MFS represent a spectrum of malignant myxoid tumors of fibroblastic origin that exhibit a range of clinical and histopathologic features.UPS is almost never a cutaneous tumor.ES is a rare, highly aggressive tumor that classically presents on the hands and fingers of young males, which can mimic nonneoplastic inflammatory lesions. SN - PB - The McGraw-Hill Companies CY - New York, NY Y2 - 2023/06/10 UR - accessmedicine.mhmedical.com/content.aspx?aid=56063111 ER -