TY - CHAP M1 - Book, Section TI - Chapter 14. Atopic Dermatitis (Atopic Eczema) A1 - Leung, Donald Y.M. A1 - Eichenfield, Lawrence F. A1 - Boguniewicz, Mark A2 - Goldsmith, Lowell A. A2 - Katz, Stephen I. A2 - Gilchrest, Barbara A. A2 - Paller, Amy S. A2 - Leffell, David J. A2 - Wolff, Klaus PY - 2012 T2 - Fitzpatrick's Dermatology in General Medicine, 8e AB - |PrintAtopic Dermatitis at a GlancePrevalence peak of 15–20% in early childhood in industrialized countries.A chronic or chronically relapsing disorder with major features of: Pruritus;Eczematous dermatitis (acute, subacute, or chronic) with typical morphology and age-specific patterns;Facial and extensor involvement in infancy; andFlexural eczema/lichenification in children and adults.Commonly associated with the following: Personal or family history of atopy (allergic rhinitis, asthma, atopic dermatitis).Xerosis/skin barrier dysfunction.Immunoglobulin E reactivity.Genetic basis influenced by environmental factors with alterations in immunologic responses in T cells, antigen processing, inflammatory cytokines, host defense proteins, allergen sensitivity, and infection. SN - PB - The McGraw-Hill Companies CY - New York, NY Y2 - 2024/04/19 UR - accessmedicine.mhmedical.com/content.aspx?aid=56024360 ER -