TY - CHAP M1 - Book, Section TI - Chapter 27. Neurophysiology & Pharmacology of the Lower Urinary Tract A1 - Andersson, Karl-Erik A2 - McAninch, Jack W. A2 - Lue, Tom F. PY - 2013 T2 - Smith & Tanagho's General Urology, 18e AB - The bladder, in concert with the urethra and the pelvic floor, is responsible for storage and periodic expulsion of urine. The integrated function of these components of the lower urinary tract (LUT) is dependent on a complex control system in the brain, spinal cord and peripheral ganglia, and on local regulatory factors (de Groat, 2006). Dysfunction of the central nervous control systems or of the components of the LUT can produce insufficient voiding and retention of urine, or different types of urinary incontinence (mainly urgency and stress incontinence), or the symptom complex of the “overactive bladder” (OAB), characterized by urgency, frequency with or without urgency incontinence, often with nocturia (Abrams et al, 2002). SN - PB - The McGraw-Hill Companies CY - New York, NY Y2 - 2024/04/20 UR - accessmedicine.mhmedical.com/content.aspx?aid=56947388 ER -