TY - CHAP M1 - Book, Section TI - Chapter 59. Poisonings & Intoxications A1 - Winchester, James F. A1 - Feinfeld, Donald A. A2 - Lerma, Edgar V. A2 - Berns, Jeffrey S. A2 - Nissenson, Allen R. PY - 2009 T2 - CURRENT Diagnosis & Treatment: Nephrology & Hypertension AB - Because of modern medical approaches mortality from poisoning is low. However, severe poisoning in certain groups of patients is associated with a high mortality: poisons with toxic metabolites (eg, methanol, ethylene glycol, and acetaminophen), poisons inducing metabolic changes (eg, salicylates), and poisons that produce deep coma (eg, phenobarbital). This chapter will discuss the role of forced diuresis and modern dialysis techniques used to treat poisoning, and will give the clinician guidance in the appropriate use of these treatments applied to drug or chemical intoxication. We will use real case reports to illustrate these points. SN - PB - The McGraw-Hill Companies CY - New York, NY Y2 - 2024/03/28 UR - accessmedicine.mhmedical.com/content.aspx?aid=6342310 ER -