TY - CHAP M1 - Book, Section TI - Chapter 50. Liver Transplantation A1 - Qamar, Amir A. A2 - Greenberger, Norton J. A2 - Blumberg, Richard S. A2 - Burakoff, Robert PY - 2012 T2 - CURRENT Diagnosis & Treatment: Gastroenterology, Hepatology, & Endoscopy, 2e AB - Hepatitis C and hepatocellular carcinoma are among the leading indications for liver transplantation in the United States.Thorough medical, psychiatric, and social evaluation is required prior to listing patients for transplantation.The Model for End-Stage Liver Disease (MELD) score is widely used for prioritizing patients on the transplant waiting list.Liver biopsy is needed to confirm the diagnosis of acute rejection, which is common and occurs in up to 60% of patients.Medical and surgical complications after transplantation can occur immediately or years later.Biliary strictures and leaks occur in 15% of patients after transplantation.Long-term immunosuppression, particularly with calcineurin inhibitors, is associated with an increased risk of renal failure. SN - PB - The McGraw-Hill Companies CY - New York, NY Y2 - 2024/04/18 UR - accessmedicine.mhmedical.com/content.aspx?aid=55961794 ER -