TY - CHAP M1 - Book, Section TI - Chapter 46. Hepatorenal Syndrome A1 - Greenberger, Norton J. A2 - Greenberger, Norton J. A2 - Blumberg, Richard S. A2 - Burakoff, Robert PY - 2012 T2 - CURRENT Diagnosis & Treatment: Gastroenterology, Hepatology, & Endoscopy, 2e AB - Type 1 hepatorenal syndrome—rapid and progressive impairment of renal function defined by doubling of the initial serum creatinine level to >2.5 mg/dL or 50% reduction of the initial 24-hour creatinine clearance to 1.5 mg/dL that does not meet the criteria for type 1.Frequent precipitants include gastrointestinal bleeding, sepsis, spontaneous bacterial peritonitis, aggressive diuresis and paracentesis, nonsteroidal anti-inflammatory drugs (NSAIDs), and intravenous contrast agents.Intravenous albumin, 1.0 g/kg, should be administered on the first day of diagnosis of hepatorenal syndrome, Type 1 followed by 20–40 g/day. SN - PB - The McGraw-Hill Companies CY - New York, NY Y2 - 2024/04/19 UR - accessmedicine.mhmedical.com/content.aspx?aid=55961390 ER -