TY - CHAP M1 - Book, Section TI - Immunization A1 - Williams, Joshua T. B. A1 - Cataldi, Jessica R. A1 - Daley, Matthew F. A1 - O’Leary, Sean T. A2 - Bunik, Maya A2 - Levin, Myron J. A2 - Abzug, Mark J. A2 - Schreiner, Teri L. PY - 2025 T2 - Current Diagnosis & Treatment: Pediatrics, 27th Edition AB - Immunization is one of the greatest public health achievements of modern times. Largely due to immunization, the annual incidences of diphtheria, paralytic poliomyelitis, measles, mumps, rubella, and Haemophilus influenzae type b (Hib) in the United States have fallen by more than 99% compared with the average annual incidences of these diseases in the 20th century. Invasive pneumococcal disease in children younger than 5 years has declined steeply since routine pneumococcal vaccination began in 2000. Similarly, rotavirus vaccination is associated with substantial declines in hospitalizations and emergency department visits for diarrheal illnesses in young children. Childhood immunization has also led, through herd immunity, to significant decreases in several infectious illnesses in adults, including pneumococcal, rotavirus, and varicella disease. The coronavirus disease 2019 (COVID-19) pandemic disrupted health care delivery and was associated with declines in routine vaccination for infants, children, and adolescents; efforts to regain these coverage losses are ongoing. SN - PB - McGraw Hill CY - New York, NY Y2 - 2025/03/15 UR - accessmedicine.mhmedical.com/content.aspx?aid=1211976224 ER -