TY - CHAP M1 - Book, Section TI - Hypertrophic Cardiomyopathy A1 - Ananthasubramaniam, Karthik A2 - Crawford, Michael H. PY - 2023 T2 - Current Diagnosis & Treatment: Cardiology, 6e AB - ESSENTIALS OF DIAGNOSISNote: Not all criteria are needed for the diagnosis of hypertrophic cardiomyopathy.Asymmetric hypertrophied nondilated ventricle with septal to posterior wall end-diastolic thickness ratio more than 1.3 not explained by other etiologies.Ejection murmur that increases with Valsalva with or without concomitant mitral regurgitation murmur and preserved aortic second sound.Increased gradients causing obstruction across left ventricular outflow tract and/or mid ventricle with characteristic late peaking “dagger”-shaped Doppler velocity profile.Mitral valve apparatus structural abnormalities and systolic anterior motion with varying degree of mitral regurgitation.Midsystolic aortic valve closure.Impaired diastolic function with decrease in tissue Doppler peak early diastolic velocity (e′) and global longitudinal strain. SN - PB - McGraw Hill Education CY - New York, NY Y2 - 2024/10/07 UR - accessmedicine.mhmedical.com/content.aspx?aid=1198113674 ER -