TY - CHAP M1 - Book, Section TI - Benign Metastasizing Leiomyoma A1 - Pacheco-Rodriguez, Gustavo A1 - Astapova, Olga I. A1 - Hammes, Stephen R. A1 - Moss, Joel A2 - Grippi, Michael A. A2 - Antin-Ozerkis, Danielle E. A2 - Dela Cruz, Charles S. A2 - Kotloff, Robert M. A2 - Kotton, Camille Nelson A2 - Pack, Allan I. PY - 2023 T2 - Fishman’s Pulmonary Diseases and Disorders, 6e AB - Benign metastasizing leiomyoma (BML) is a rare disease of women. It is characterized by noninvasive, nonaggressive, well-circumscribed, single or multiple tumors composed of differentiated smooth muscle cells, localized to sites other than the uterus in patients with uterine leiomyomas1–7 and, in some cases, adnexal tumors.8 BML has been identified in lungs3 and lymph nodes9 which, in addition to uterine leiomyomas, are the most common sites involved. BMLs have also been identified in the mediastinum,10,11 retroperitoneum,12 vascular channels,13 bone,14,15 heart,16 skeletal muscle,17 spine,18 and pancreas.19 Pulmonary BML is usually asymptomatic and presents with either single or multiple lung nodules of varying sizes20 found incidentally on chest x-ray or computed tomography (CT) imaging. Occasionally, patients present with mild or severe pulmonary symptoms due to BML. Most patients with BML have undergone uterine myomectomy or hysterectomy due to leiomyomas.3,6,21,22 SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/04/19 UR - accessmedicine.mhmedical.com/content.aspx?aid=1195006612 ER -