TY - CHAP M1 - Book, Section TI - Drug Discovery: From Medicinal Plants to Computer-Aided Drug Design A1 - Gilson, Michael K. A1 - Brunton, Laurence L. A2 - Brunton, Laurence L. A2 - Knollmann, Björn C. PY - 2023 T2 - Goodman & Gilman's: The Pharmacological Basis of Therapeutics, 14th Edition AB - The first edition of Goodman & Gilman, published in 1941, helped to organize the field of pharmacology, giving it intellectual validity and an academic identity. That edition began: “The subject of pharmacology is a broad one and embraces the knowledge of the source, physical and chemical properties, compounding, physiological actions, absorption, fate, and excretion, and therapeutic uses of drugs. A drug may be broadly defined as any chemical agent that affects living protoplasm, and few substances would escape inclusion by this definition.” In practice, of course, a chemical or biological agent is considered a legal drug only if it has been approved as such by a national regulatory agency, such as the U.S. Food and Drug Administration (FDA) or the European Medicines Agency; these approved compounds are the focus of this book. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/28 UR - accessmedicine.mhmedical.com/content.aspx?aid=1193226136 ER -