TY - CHAP M1 - Book, Section TI - Rickets & Osteomalacia A1 - Fitzgerald, Paul A. A2 - Papadakis, Maxine A. A2 - McPhee, Stephen J. A2 - Rabow, Michael W. A2 - McQuaid, Kenneth R. PY - 2023 T2 - Current Medical Diagnosis & Treatment 2023 AB - ESSENTIALS OF DIAGNOSISLow bone density from defective mineralization.Caused by deficiency in calcium, phosphorus, or low alkaline phosphatase.Rickets: defective bone mineralization in childhood or adolescence before epiphyseal fusion.Osteomalacia: defective bone mineralization in adults with fused epiphyses.Painful proximal muscle weakness (especially pelvic girdle); bone pain.Low serum 25-hydroxy-vitamin D (25-OHD), hypocalcemia, hypocalciuria, hypophosphatemia, secondary hyperparathyroidism.Classic radiologic features may be present. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/28 UR - accessmedicine.mhmedical.com/content.aspx?aid=1193160621 ER -