TY - CHAP M1 - Book, Section TI - HIV-Associated Nephropathy A1 - Dirkx, Tonja C. A1 - Woodell, Tyler B. A2 - Papadakis, Maxine A. A2 - McPhee, Stephen J. A2 - Rabow, Michael W. A2 - McQuaid, Kenneth R. PY - 2023 T2 - Current Medical Diagnosis & Treatment 2023 AB - HIV-associated nephropathy usually presents with nephrotic syndrome and declining GFR in patients with active HIV infection. Most who present with HIV-associated nephropathy are of sub-Saharan African descent with APOL1 risk alleles (see section on Focal Segmental Glomerulosclerosis). HIV-associated nephropathy is usually associated with low CD4 counts and AIDS, but it can also be the initial presentation of HIV disease. Persons living with HIV are at risk for other kidney diseases, such as toxicity from antiretroviral medications (eg, tenofovir disoproxil fumarate), vascular disease, and diabetes, or an immune complex–mediated glomerular disease (HIV-immune complex disease). SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/04/23 UR - accessmedicine.mhmedical.com/content.aspx?aid=1193127639 ER -