TY - CHAP M1 - Book, Section TI - HIV Infection & AIDS Year in Review A1 - Papadakis, Maxine A. A1 - McPhee, Stephen J. A1 - Rabow, Michael W. A1 - McQuaid, Kenneth R. PY - 2023 T2 - Current Medical Diagnosis & Treatment 2023 AB - In the ANCHOR study, which involved nearly 4500 individuals with anal high-grade squamous intraepithelial lesions (HGSIL), nine patients who were assigned to aggressive therapy (mostly office-based electrocautery) developed anal cancer compared with 21 of those in an active monitoring group, representing a 57% decrease in relative risk over the median 25.8-month follow-up period. This pivotal study will change care toward more aggressive screening for HGSIL and treatment to prevent progression to anal cancer. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/04/19 UR - accessmedicine.mhmedical.com/content.aspx?aid=1193123618 ER -