TY - CHAP M1 - Book, Section TI - Lefamulin A1 - Gruenberg, Katherine A1 - Guglielmo, B. Joseph A2 - Papadakis, Maxine A. A2 - McPhee, Stephen J. A2 - Rabow, Michael W. A2 - McQuaid, Kenneth R. PY - 2023 T2 - Current Medical Diagnosis & Treatment 2023 AB - Lefamulin, the only commercially available antibiotic from the pleuromutilin class, is used in community-acquired bacterial pneumonia. Lefamulin is active against Streptococcus pneumoniae, Haemophilus influenzae, Moraxella catarrhalis, atypical bacteria (eg, Mycoplasma pneumoniae, Chlamydophila pneumoniae, and Legionella pneumophila), Staphylococcus aureus (including methicillin-resistant strains), Enterococcus faecium (including vancomycin-resistant strains), and Streptococcus pyogenes. It lacks appreciable activity against Enterobacteriaceae and Pseudomonas aeruginosa. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/28 UR - accessmedicine.mhmedical.com/content.aspx?aid=1193122095 ER -