TY  - CHAP
M1  - Book, Section
TI  - Treatment of Central Nervous System Degenerative Disorders
A1  - Roberson, Erik D.
A1  - Yacoubian, Talene A.
A2  - Brunton, Laurence L.
A2  - Knollmann, Björn C.
PY  - 2023
T2  - Goodman & Gilman's: The Pharmacological Basis of Therapeutics, 14th Edition
AB  - AbbreviationsAADC:  aromatic  L-amino  acid  decarboxylaseAβ:  amyloid  βACh:  acetylcholineAChE:  acetylcholinesteraseAD:  Alzheimer’s  diseaseALDH:  aldehyde  dehydrogenaseALS:  amyotrophic  lateral  sclerosisapoE:  apolipoprotein  EAPP:  amyloid  precursor  proteinARIA:  amyloid-related  imaging  abnormalityASO:  antisense  oligonucleotidesBPSD:  behavioral  and  psychiatric  symptoms  in  dementiaBuChE:  butyrylcholinesteraseCNS:  central  nervous  systemCOMT:  catechol-O-methyltransferaseCSF:  cerebrospinal  fluidDA:  dopamineDAT:  DA  transporterDβH:  dopamine-β-hydroxylaseDOPAC:  3,4-dihydroxyphenylacetic  acidFALS:  familial  ALSGABA:  γ-aminobutyric  acidGBA:  β-glucocerebrosidaseGI:  gastrointestinalGlu:  glutamatergicGPCR:  G  protein-coupled  receptorGPe:  globus  pallidus  externGPi:  globus  pallidus  internaHD:  Huntington’s  disease5HT:  serotoninHTT:  huntingtinHVA:  homovanillic  acidICD:  impulse  control  disorderLRRK2:  leucine-rich  repeat  kinase  2MAO:  monoamine  oxidaseMCI:  mild  cognitive  impairmentMPTP:N-methyl-4-phenyl-1,2,3,6-tetrahydropyridineMRI:  magnetic  resonance  imaging3MT:  3-methoxyltyramineNIA-AA:  National  Institute  on  Aging  and  Alzheimer’s  AssociationNE:  norepinephrineNET:  NE  transporterNMDA:N-methyl-D-aspartate3-OMD:  3-O-methyl  dopaPD:  Parkinson’s  diseasePET:  positron  emission  tomographyPH:  phenylalanine  hydroxylaseREM:  rapid  eye  movementSNpc:  substantia  nigra  pars  compactaSNpr:  substantia  nigra  pars  reticulateSOD:  superoxide  dismutaseSSRI:  selective  serotonin  reuptake  inhibitorSTN:  subthalamic  nucleusTAR:  transactivation  response  elementTDP-43:  TAR  DNA-binding  protein  43TH:  tyrosine  hydrolaseVA/VL:  ventroanterior  and  ventrolateralVMAT2:  vesicular  monoamine  transporter  2  
SN  - 
PB  - McGraw-Hill Education
CY  - New York, NY
Y2  - 2024/04/23
UR  - accessmedicine.mhmedical.com/content.aspx?aid=1193230203
ER  -