TY - CHAP M1 - Book, Section TI - Pruritus in Patients with No Underlying Skin Disease A1 - Ahmed, Rehana A2 - Soutor, Carol A2 - Hordinsky, Maria K. PY - 2022 T2 - Clinical Dermatology: Diagnosis and Management of Common Disorders, 2e AB - Pruritus (itch) is the unpleasant sensation of the skin that results in an urge to scratch. It is a major symptom of many cutaneous and systemic diseases. Pruritus can range from mild to severe and may be intermittent or chronic (lasting longer than 6 weeks). Pruritus can have a significant impact on health-related quality of life (HRQOL), and has been associated with depression, decreased sleep quality, and a negative impact on most quality of life categories.1 The authors of a case-control study of patients with chronic pruritus observed that the impact of chronic pruritus on HRQOL may be similar to that of chronic pain.2 Pruritus has multiple etiologies in patients with and without underlying skin disease. The International Forum for the Study of Itch recently published a clinical classification of pruritus 3 in which they proposed six categories for pruritus based on the underlying origin: SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/28 UR - accessmedicine.mhmedical.com/content.aspx?aid=1190939080 ER -