TY - CHAP M1 - Book, Section TI - Ventricular Arrhythmias and Sudden Cardiac Death A1 - Hayase, Justin A1 - Shivkumar, Kalyanam A1 - Bradfield, Jason S. A2 - Fuster, Valentin A2 - Narula, Jagat A2 - Vaishnava, Prashant A2 - Leon, Martin B. A2 - Callans, David J. A2 - Rumsfeld, John S. A2 - Poppas, Athena PY - 2022 T2 - Fuster and Hurst's The Heart, 15e AB - Chapter SummaryThis chapter discusses the epidemiology and pathophysiology of sudden cardiac death (SCD), which is most often caused by ventricular arrhythmias, and addresses some of the key considerations for the evaluation and treatment of ventricular arrhythmias. Major risk factors for developing these arrhythmias include cardiac structural abnormalities and coronary artery disease (CAD) (see Fuster and Hurst’s Central Illustration). Moreover, a number of inherited channelopathies can predispose to these arrhythmias and should be considered in the context of a structurally normal heart. Ventricular arrhythmias can range from idiopathic premature ventricular complexes, to monomorphic ventricular tachycardia (VT), to ventricular fibrillation (VF). Management of ventricular arrhythmias requires a comprehensive approach that may involve multiple therapies, including an implantable cardioverter defibrillator (ICD), antiarrhythmic medications, catheter ablation, and/or autonomic modulation. The decision-making process for management depends highly upon the presence of underlying structural abnormalities. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/04/18 UR - accessmedicine.mhmedical.com/content.aspx?aid=1202447458 ER -