TY - CHAP M1 - Book, Section TI - Hypopituitarism A1 - Melmed, Shlomo A1 - Jameson, J. Larry A2 - Loscalzo, Joseph A2 - Fauci, Anthony A2 - Kasper, Dennis A2 - Hauser, Stephen A2 - Longo, Dan A2 - Jameson, J. Larry PY - 2022 T2 - Harrison's Principles of Internal Medicine, 21e AB - Deficient production of anterior pituitary hormones leads to features of hypopituitarism. Impaired production of one or more of the anterior pituitary trophic hormones can result from inherited disorders; more commonly, adult hypopituitarism is acquired and reflects the compressive mass effects of tumors or the consequences of local pituitary or hypothalamic traumatic, autoimmune, inflammatory, or vascular damage. These processes also may impair synthesis or secretion of hypothalamic hormones, with resultant pituitary failure (Table 379-1). SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/28 UR - accessmedicine.mhmedical.com/content.aspx?aid=1198715197 ER -