TY - CHAP M1 - Book, Section TI - Acute Respiratory Distress Syndrome A1 - Baron, Rebecca M. A1 - Levy, Bruce D. A2 - Loscalzo, Joseph A2 - Fauci, Anthony A2 - Kasper, Dennis A2 - Hauser, Stephen A2 - Longo, Dan A2 - Jameson, J. Larry PY - 2022 T2 - Harrison's Principles of Internal Medicine, 21e AB - Acute respiratory distress syndrome (ARDS) is a clinical syndrome of severe dyspnea of rapid onset, hypoxemia, and diffuse pulmonary infiltrates leading to respiratory failure. ARDS can be caused by diffuse lung injury from many underlying medical and surgical disorders. The lung injury may be direct, as occurs in toxic inhalation, or indirect, as occurs in sepsis (Table 301-1). The clinical features of ARDS are listed in Table 301-2. By expert consensus, ARDS is defined by three categories based on the degrees of hypoxemia (Table 301-2). These stages of mild, moderate, and severe ARDS are associated with mortality risk and with the duration of mechanical ventilation in survivors. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/28 UR - accessmedicine.mhmedical.com/content.aspx?aid=1198710091 ER -