TY  - CHAP
M1  - Book, Section
TI  - Genes in Families
A1  - Pyeritz, Reed E.
A2  - Papadakis, Maxine A.
A2  - McPhee, Stephen J.
A2  - Rabow, Michael W.
A2  - McQuaid, Kenneth R.
PY  - 2022
T2  - Current Medical Diagnosis & Treatment 2022
AB  - Since  the  first  decade  of  the  twentieth  century,  the  patterns  of  recurrence  of  specific  human  phenotypes  have  been  explained  in  terms  of  principles  first  described  by  Mendel  in  the  garden  pea  plant.  Mendel's  second  principle—usually  referred  to  as  his  first1—is  called  the  law  of  segregation  and  states  that  a  pair  of  factors  (alleles)  that  determines  some  trait  separates  (segregates)  during  formation  of  gametes.  In  simple  terms,  a  heterozygous  (A/a)  person  will  produce  two  types  of  gametes  with  respect  to  this  locus—one  containing  only  A  and  one  containing  only  a,  in  equal  proportions.  Offspring  of  this  person  will  have  a  50–50  chance  of  inheriting  the  A  allele  and  a  similar  chance  of  inheriting  the  a  allele.  
SN  - 
PB  - McGraw-Hill Education
CY  - New York, NY
Y2  - 2024/04/19
UR  - accessmedicine.mhmedical.com/content.aspx?aid=1184181581
ER  -