TY - CHAP M1 - Book, Section TI - Overview: Genetic & Genomic Disorders A1 - Pyeritz, Reed E. A2 - Papadakis, Maxine A. A2 - McPhee, Stephen J. A2 - Rabow, Michael W. A2 - McQuaid, Kenneth R. PY - 2022 T2 - Current Medical Diagnosis & Treatment 2022 AB - Human genetics is the scientific study of the variations among people that are determined by the heritable units called genes, and how variations due to genes occur and are transmitted in individuals, families, and populations. While the discipline of genetics had its origins with Gregor Mendel in the mid-nineteenth century, human genetics began in the early twentieth century and remains one of the most vibrant of the biologic sciences. Genomics, on the other hand, had its origins much more recently, the term first being coined in 1986, and subsumes the study of the organization, function, and interpretation of all of an organism's genetic material. Genomics has largely been stimulated and driven by technologies that enable the sequencing of DNA and the comparative analysis of vast amounts of sequence data. Both fields are transforming our understanding of human biology, medicine, and public health. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/28 UR - accessmedicine.mhmedical.com/content.aspx?aid=1184181526 ER -