TY - CHAP M1 - Book, Section TI - Spotted Fevers A1 - Clark, Eva A1 - Akamine, Christine A1 - Shandera, Wayne X. A2 - Papadakis, Maxine A. A2 - McPhee, Stephen J. A2 - Rabow, Michael W. A2 - McQuaid, Kenneth R. PY - 2022 T2 - Current Medical Diagnosis & Treatment 2022 AB - ESSENTIALS OF DIAGNOSISExposure to tick bite in an endemic area.Influenza-like prodrome followed by fever, severe headache, and myalgias; occasionally, delirium and coma.Red macular rash appears between days 2 and 6 of fever, first on the wrists and ankles and then spreading centrally; it may become petechial.Mortality over 70% in untreated patients.Serial serologic examinations by indirect fluorescent antibody confirm the diagnosis retrospectively. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/29 UR - accessmedicine.mhmedical.com/content.aspx?aid=1184168138 ER -