TY - CHAP M1 - Book, Section TI - Medullary Sponge Kidney A1 - Dirkx, Tonja C. A1 - Woodell, Tyler B. A2 - Papadakis, Maxine A. A2 - McPhee, Stephen J. A2 - Rabow, Michael W. A2 - McQuaid, Kenneth R. PY - 2022 T2 - Current Medical Diagnosis & Treatment 2022 AB - Medullary sponge kidney is believed to affect less than 1% of the general population. Although present at birth, it is not usually diagnosed until the fourth or fifth decade. It is thought to occur due to disruption of the ureteric bud-metanephric mesenchyme interface, often resulting from autosomal dominant mutations in genes responsible for urogenital development. Kidneys have a marked irregular enlargement of the medullary and interpapillary collecting ducts. This is associated with medullary cysts that are diffuse, giving a “Swiss cheese” appearance in these regions. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/04/19 UR - accessmedicine.mhmedical.com/content.aspx?aid=1184183496 ER -