TY - CHAP M1 - Book, Section TI - Kidney Biopsy A1 - Dirkx, Tonja C. A1 - Woodell, Tyler B. A2 - Papadakis, Maxine A. A2 - McPhee, Stephen J. A2 - Rabow, Michael W. A2 - McQuaid, Kenneth R. PY - 2022 T2 - Current Medical Diagnosis & Treatment 2022 AB - Indications for percutaneous needle biopsy include (1) unexplained AKI or CKD; (2) unexplained proteinuria or hematuria, or both; (3) previously identified and treated lesions to guide future therapy; (4) systemic diseases associated with kidney dysfunction, such as systemic lupus erythematosus (SLE), anti-GBM disease, and granulomatosis with polyangiitis (eFigure 22–3); and (5) kidney transplant dysfunction, to evaluate for transplant rejection or other abnormalities. Kidney biopsies should only be performed if the results will influence the treatment plan or facilitate discussion about prognosis. Relative contraindications include a solitary or ectopic kidney (exception for transplant allografts), horseshoe kidney, ESKD, congenital anomalies, and multiple cysts. Absolute contraindications include an uncorrected bleeding disorder; severe uncontrolled hypertension; renal infection or neoplasm; hydronephrosis; or uncooperative patients, including those who are unable to lie flat for the procedure. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/04/19 UR - accessmedicine.mhmedical.com/content.aspx?aid=1184182923 ER -