TY - CHAP M1 - Book, Section TI - Stem Cell & Immune Cell Therapeutics A1 - Damon, Lloyd E. A1 - Andreadis, Charalambos Babis A2 - Papadakis, Maxine A. A2 - McPhee, Stephen J. A2 - Rabow, Michael W. A2 - McQuaid, Kenneth R. PY - 2022 T2 - Current Medical Diagnosis & Treatment 2022 AB - Hematopoietic stem cell transplantation is a valuable treatment for a variety of hematologic malignancies and a few nonhematologic cancers and nonmalignant conditions. In many cases, stem cell transplantation offers the only curative option and can be a life-saving procedure. Immune effector cell (eg, T-cell, NK-cell) transplantation is an emerging approach in hematologic and solid malignancies that utilizes immune cells genetically engineered to recognize cancer-specific epitopes and incite an immune response against cancer. Autologous-derived T-cell therapies targeting CD19 are FDA approved for the treatment of aggressive lymphomas. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/28 UR - accessmedicine.mhmedical.com/content.aspx?aid=1184166474 ER -