TY - CHAP M1 - Book, Section TI - Anthrax A1 - Hendricks, Katherine A. A1 - Vieira, Antonio A2 - Boulton, Matthew L. A2 - Wallace, Robert B. PY - 2022 T2 - Maxcy-Rosenau-Last Public Health & Preventive Medicine, 16e AB - Background. Anthrax, caused by the bacterium Bacillus anthracis, has been recognized as an infectious disease of both humans and animals for many centuries. While no longer causing substantial disease in the United States, it occurs in multiple countries worldwide and is a major bioterrorist threat. The name of the disease, “anthrax,” is derived from the Greek word anthrakos, meaning charcoal or carbuncle, and refers to the black skin lesions commonly seen with cutaneous anthrax infection.1 Anthrax is likely to have originated over 6000 years ago in ancient Mesopotamia and Egypt, where it may have caused the fifth plague of Egypt in which the “horses, donkeys, and camels and cattle, sheep, and goats” of the Egyptians died the same day.2 However it may have existed as long as 12,000 years ago, when livestock were first domesticated.1,3 The Roman poet Virgil described an anthrax epizootic, observing that eating meat or wearing clothes made from the wool or hides of infected animals resulted in human anthrax.4 Devastating epizootics of anthrax were described in the middle ages, and an outbreak of anthrax referred to as the “black bain” is reported to have killed 60,000 people in Europe in 1613.5 A number of notable historical6–8 as well as recent9,10 outbreaks have occurred in the wake of famines or food shortages. SN - PB - McGraw Hill CY - New York, NY Y2 - 2024/04/18 UR - accessmedicine.mhmedical.com/content.aspx?aid=1182667574 ER -