TY - CHAP M1 - Book, Section TI - Herpes Simplex Virus A1 - Alsulami, Abdulsalam A1 - Whitley, Richard J. A2 - Boulton, Matthew L. A2 - Wallace, Robert B. PY - 2022 T2 - Maxcy-Rosenau-Last Public Health & Preventive Medicine, 16e AB - Herpes simplex virus (HSV) is one of the most common infections encountered by humans worldwide. As a member of the herpesvirus family (Herpesviridae), it shares the unique biologic characteristic of being able to exist in a latent state and recur periodically, if not chronically, serving as a reservoir for transmission from one person to another. There are two distinct antigenic types of HSV; HSV-1 and HSV-2. HSV-1 is usually associated with infections above the belt, namely involving the oropharynx and lips; however, a large and increasing number of genital infections in the United States is attributed to HSV-1. HSV-2 routinely causes infections below the belt, involving the genitalia, buttocks, and infrequently the lower extremities. In addition, both viruses can cause infection of the newborn. The spectrum of disease caused by HSV ranges from benign and nuisance infections to those that can be life threatening.1 SN - PB - McGraw Hill CY - New York, NY Y2 - 2024/03/29 UR - accessmedicine.mhmedical.com/content.aspx?aid=1182665892 ER -