TY  - CHAP
M1  - Book, Section
TI  - Developmental Disabilities
A1  - Paneth, Nigel
A2  - Boulton, Matthew L.
A2  - Wallace, Robert B.
PY  - 2022
T2  - Maxcy-Rosenau-Last Public Health & Preventive Medicine, 16e
AB  - The  human  species  is  altricial  in  comparison  to  other  large  mammals,  including  large  primates,  and  has  only  a  modest  supply  of  motor  and  cognitive  skills  at  birth.  The  anatomic  substrates  of  cognition,  behavior,  and  movement  are  largely  set  down  in  utero,  but  their  full  functional  expression  takes  many  years.  Alterations  in  patterns  of  in-utero  brain  development,  whether  fashioned  by  genetic  abnormalities,  by  damage  from  environmental  exposures,  or  by  the  interaction  of  these  two  forces,  can  damage  this  anatomic  substrate  without  altering  early  developmental  trajectories  in  any  substantial  way.  Children  born  lacking  major  cortical  structures,  as  in  hydranencephaly,  are  often  incapable  of  expressing  the  full  repertoire  of  typical  human  newborn  behavior.1  
SN  - 
PB  - McGraw Hill
CY  - New York, NY
Y2  - 2024/04/24
UR  - accessmedicine.mhmedical.com/content.aspx?aid=1182668706
ER  -