TY - CHAP M1 - Book, Section TI - Cannabinoid Drugs A1 - Katzung, Bertram G. A1 - Kruidering-Hall, Marieke A1 - Tuan, Rupa Lalchandani A1 - Vanderah, Todd W. A1 - Trevor, Anthony J. PY - 2021 T2 - Katzung & Trevor's Pharmacology: Examination & Board Review, 13e AB - Currently available cannabinoid drugs consist of one major subgroup that act at the CB1 receptors. However, there are rapidly developing alternative groups of drugs that target newly discovered receptors as well as new drugs that are designed to enrich endogenous cannabinoids.Delta-9-tetrahydrocannabinol (THC) may be considered the prototype that acts directly at both CB1 and CB2 receptors. However, THC has made little progress in clinical use due to the psychoactive component, which is thought to be due mainly to action at the CB1 receptor. Novel cannabinoids are being discovered that lack this unwanted (in clinical usage) effect. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/04/16 UR - accessmedicine.mhmedical.com/content.aspx?aid=1180559343 ER -