TY - CHAP M1 - Book, Section TI - Cell Death A1 - Glennon, Elizabeth K.K. A1 - Vijayan, Kamalakannan A1 - Kaushansky, Alexis A2 - Kaushansky, Kenneth A2 - Prchal, Josef T. A2 - Burns, Linda J. A2 - Lichtman, Marshall A. A2 - Levi, Marcel A2 - Linch, David C. PY - 2021 T2 - Williams Hematology, 10e AB - SUMMARYThe survival or death of individual cells is paramount to a myriad of biological processes in metazoans. Although it is thought that some cells die “accidently” in a nonprogrammed manner, many biological processes depend on orchestrated processes of cell death, collectively called “regulated cell death.” This collection of cell death processes imparts consequences not only on the dying cell but also on the surrounding cells and tissues. Current work has not only described this compendium of cell death processes in detail but has also identified scenarios in which cell death is not actually the end of cellular activities. For example, evidence indicates that in the case of infection, the pathogen can survive after the cell has died. This chapter discusses some of the ways by which cells die in a regulated manner and the downstream consequences of these death processes. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/28 UR - accessmedicine.mhmedical.com/content.aspx?aid=1180477163 ER -