TY - CHAP M1 - Book, Section TI - Acute Kidney Injury A1 - Slawski, Barbara A1 - Vasudev, Brahm A2 - Cohn, Steven L. PY - 2021 T2 - Decision Making in Perioperative Medicine: Clinical Pearls AB - Acute kidney injury (AKI) is defined as an acute and potentially reversible decline in the kidney function/glomerular filtration rate (GFR) that occurs over hours to days. It represents a spectrum of kidney injury ranging from mild to more severe forms of injury requiring renal replacement therapy (RRT). While AKI can occur in patients with normal kidney function, patients with a history of chronic kidney disease (CKD) are at higher risk (AKI on CKD). The Kidney Disease: Improving Global Outcomes (KDIGO) criteria are now accepted worldwide as the criteria for defining AKI (Table 40-1).1 Although AKI is more common after cardiac surgery, its incidence after noncardiac surgery is high as well. Even small postoperative increases in creatinine are associated with several adverse outcomes including higher rates of morbidity, mortality, cardiovascular events, longer lengths of stay, cost, and poor surgical outcomes. SN - PB - McGraw Hill CY - New York, NY Y2 - 2024/04/19 UR - accessmedicine.mhmedical.com/content.aspx?aid=1179531932 ER -