TY  - CHAP
M1  - Book, Section
TI  - Agents That Affect Bone Mineral Homeostasis
A1  - Katzung, Bertram G.
A1  - Kruidering-Hall, Marieke
A1  - Trevor, Anthony J.
PY  - 2019
T2  - Katzung & Trevor's Pharmacology: Examination & Board Review, 12e
AB  - Calcium  and  phosphorus,  the  2  major  elements  of  bone,  are  crucial  not  only  for  the  mechanical  strength  of  the  skeleton  but  also  for  the  normal  function  of  many  other  cells  in  the  body.  Three  hormones  are  the  main  regulators  of  calcium  and  phosphate  homeostasis,  parathyroid  hormone  (PTH),  vitamin  D,  and  fibroblast  growth  factor  23  (FGF23)  (Figure  42–1).  Calcitonin,  glucocorticoids,  and  estrogens  play  secondary  roles.  These  hormones,  or  drugs  that  mimic  or  suppress  their  actions,  are  used  in  the  treatment  of  bone  mineral  disorders  (eg,  osteoporosis,  rickets,  osteomalacia,  Paget’s  disease),  as  are  several  nonhormonal  agents.  
SN  - 
PB  - McGraw-Hill Education
CY  - New York, NY
Y2  - 2024/04/19
UR  - accessmedicine.mhmedical.com/content.aspx?aid=1179223629
ER  -