TY - CHAP M1 - Book, Section TI - Introduction to CNS Pharmacology A1 - Katzung, Bertram G. A1 - Kruidering-Hall, Marieke A1 - Trevor, Anthony J. PY - 2019 T2 - Katzung & Trevor's Pharmacology: Examination & Board Review, 12e AB - Drugs that act on the central nervous system (CNS) are the most commonly prescribed drugs in current use. Most of these drugs act by changing ion flow through transmembrane channels of nerve cells. Transmitter reuptake transporters constitute a second class of drug targets, especially for antidepressant agents. Inhibition of acetylcholine metabolism is the major action of the drugs currently approved for use in Alzheimer’s disease and GABA metabolism is inhibited by an anticonvulsant agent. Finally, a few drugs appear to act by altering the function of neuroglia; these satellite cells support neurons metabolically and may also modulate transmitter synthesis and disposition. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/29 UR - accessmedicine.mhmedical.com/content.aspx?aid=1179218676 ER -