TY  - CHAP
M1  - Book, Section
TI  - Paget Disease of Bone
A1  - Keller, Sarah F.
A1  - Bolster, Marcy B.
A2  - Stone, John H.
PY  - 2021
T2  - Current Diagnosis & Treatment: Rheumatology, 4e
AB  - Paget  disease  of  bone  (PDB)  is  a  striking  disorder  of  aging  bone,  first  described  by  Sir  James  Paget  in  1876  in  his  paper  entitled  “On  a  Form  of  Chronic  Inflammation  of  Bones  (Osteitis  Deformans)  (Paget,  1876).”  In  that  sentinel  paper,  Paget  catalogued  the  progressive  deformity  of  bone  that  occurred  over  26  years  in  one  man,  detailing  the  enlargement  of  the  head,  the  settling  of  the  skull  over  the  spine,  the  evolving  rigidity  of  the  spine,  and  bowing  of  the  lower  limbs.  “The  shape  and  habitual  posture  of  the  patient  were  thus  made  strange  and  peculiar  (Paget,  1876).”  Paget  attributed  these  skeletal  changes  to  chronic  inflammation  of  the  affected  bones,  and  called  the  disease  osteitis  deformans,  writing  “a  better  name  may  be  given  when  more  is  known  of  it  (Paget,  1876).”  
SN  - 
PB  - McGraw Hill
CY  - New York, NY
Y2  - 2024/04/24
UR  - accessmedicine.mhmedical.com/content.aspx?aid=1180198993
ER  -