TY  - CHAP
M1  - Book, Section
TI  - Lyme Disease
A1  - Bockenstedt, Linda K.
A1  - Belperron, Alexia A.
A2  - Stone, John H.
PY  - 2021
T2  - Current Diagnosis & Treatment: Rheumatology, 4e
AB  - ESSENTIALS  OF  DIAGNOSISLyme  borreliosis  should  be  considered  in  individuals  who  have  a  reasonable  risk  of  exposure  to  Borrelia  burgdorferi-infected  ticks  and  who  present  with  a  characteristic  complex  of  signs  and  symptoms.Classic  clinical  features  occur  in  stages:Early  localized  infection  (3–30  days  after  tick  bite):  a  single  hallmark  skin  lesion  erythema  migrans  (EM),  occasionally  associated  with  fever,  malaise,  headache,  arthralgias,  and  myalgias.  These  constitutional  symptoms  can  occur  in  the  absence  of  EM,  but  this  is  unusual.Early  disseminated  infection  (weeks  to  a  few  months  after  tick  bite):  signs  include  multiple  EM  lesions,  often  with  associated  fever,  migratory  arthralgias,  and  myalgias;  carditis  manifested  primarily  as  AV  nodal  block;  neurologic  features,  including  cranial  nerve  palsies  (especially  involving  the  facial  nerve),  lymphocytic  meningitis,  and  radiculoneuropathies.Late  infection  (several  months  to  years  after  tick  bite):  arthritis,  including  monoarticular  and  migratory  pauciarticular  arthritis;  rarely  neurologic  features  such  as  peripheral  neuropathies  or  chronic  mild  encephalopathy.Supporting  serologic  evidence  of  exposure  to  B  burgdorferi  is  present  in  the  majority  of  cases  but  can  be  absent  in  early  infection.  
SN  - 
PB  - McGraw Hill
CY  - New York, NY
Y2  - 2024/04/20
UR  - accessmedicine.mhmedical.com/content.aspx?aid=1180198260
ER  -