TY  - CHAP
M1  - Book, Section
TI  - Hyperkalemia
A1  - Mount, David B.
A2  - Jameson, J. Larry
A2  - Fauci, Anthony S.
A2  - Kasper, Dennis L.
A2  - Hauser, Stephen L.
A2  - Longo, Dan L.
A2  - Loscalzo, Joseph
PY  - 2018
T2  - Harrison's Principles of Internal Medicine, 20e
AB  - Hyperkalemia  is  defined  as  a  plasma  potassium  level  of  5.5  mM,  occurring  in  up  to  10%  of  hospitalized  patients;  severe  hyperkalemia  (>6.0  mM)  occurs  in  ~1%,  with  a  significantly  increased  risk  of  mortality.  Although  redistribution  and  reduced  tissue  uptake  can  acutely  cause  hyperkalemia,  a  decrease  in  renal  K+  excretion  is  the  most  frequent  underlying  cause  (Table  49-5).  Excessive  intake  of  K+  is  a  rare  cause,  given  the  adaptive  capacity  to  increase  renal  secretion;  however,  dietary  intake  can  have  a  major  effect  in  susceptible  patients,  e.g.,  diabetics  with  hyporeninemic  hypoaldosteronism  and  chronic  kidney  disease.  Drugs  that  impact  on  the  renin-angiotensin-aldosterone  axis  are  also  a  major  cause  of  hyperkalemia.  
SN  - 
PB  - McGraw-Hill Education
CY  - New York, NY
Y2  - 2024/04/16
UR  - accessmedicine.mhmedical.com/content.aspx?aid=1178487224
ER  -