TY - CHAP M1 - Book, Section TI - Drug Receptors & Pharmacodynamics A1 - Zastrow, Mark von A2 - Katzung, Bertram G. A2 - Vanderah, Todd W. PY - 2021 T2 - Basic & Clinical Pharmacology, 15e AB - CASE STUDYA 51-year-old man presents to the emergency department due to acute difficulty breathing. The patient is afebrile and normotensive but anxious, tachycardic, and markedly tachypneic. Auscultation of the chest reveals diffuse wheezes. The physician provisionally makes the diagnosis of bronchial asthma and administers epinephrine by intramuscular injection, improving the patient’s breathing over several minutes. A normal chest X-ray and electrocardiogram are subsequently obtained, and the medical history is remarkable only for mild hypertension that is being treated with propranolol. The physician instructs the patient to discontinue use of propranolol, and changes the patient’s antihypertensive medication to verapamil. Why is the physician correct to discontinue propranolol? Why is verapamil a better choice for managing hypertension in this patient? What alternative treatment change might the physician consider? SN - PB - McGraw-Hill CY - New York, NY Y2 - 2024/03/19 UR - accessmedicine.mhmedical.com/content.aspx?aid=1176461337 ER -