TY - CHAP M1 - Book, Section TI - Cutaneous Small-Vessel Vasculitis A1 - Hardin, J. Matthew A2 - Knoop, Kevin J. A2 - Stack, Lawrence B. A2 - Storrow, Alan B. A2 - Thurman, R. Jason PY - 2021 T2 - The Atlas of Emergency Medicine, 5e AB - Cutaneous small-vessel vasculitis (CSVV) represents the deposition of immune complexes in small blood vessels with subsequent vessel damage and blood extravasation (pathologically described as leukocytoclastic vasculitis). Nonblanching, purpuric macules and initially erythematous papules frequently coalesce into violaceous plaques (“palpable purpura”). The lower extremities and dependent areas of the back and buttocks are frequently involved. Pruritus can be significant or not present. Vesicles, ulcers, and necrosis may evolve within the purpuric lesions. Lesions appear over a few days and usually resolve with hyperpigmentation over 4 to 6 weeks. Symptoms may be minimal or include fever, arthralgias, myalgias, and malaise. SN - PB - McGraw-Hill CY - New York, NY Y2 - 2024/03/28 UR - accessmedicine.mhmedical.com/content.aspx?aid=1181043936 ER -