TY  - CHAP
M1  - Book, Section
TI  - Gout & The Kidney
A1  - Dirkx, Tonja C.
A1  - Woodell, Tyler B.
A2  - Papadakis, Maxine A.
A2  - McPhee, Stephen J.
A2  - Rabow, Michael W.
PY  - 2021
T2  - Current Medical Diagnosis & Treatment 2021
AB  - The  kidney  is  the  primary  organ  for  excretion  of  uric  acid.  Patients  with  proximal  tubular  dysfunction  have  decreased  excretion  of  uric  acid  and  are  more  prone  to  gouty  arthritis  attacks.  Depending  on  the  pH  and  uric  acid  concentration,  deposition  can  occur  in  the  tubules,  the  interstitium,  or  the  urinary  tract.  The  more  alkaline  pH  of  the  interstitium  causes  urate  salt  deposition,  whereas  the  acidic  environment  of  the  tubules  and  urinary  tract  causes  uric  acid  crystal  deposition  at  high  concentrations.  
SN  - 
PB  - McGraw-Hill Education
CY  - New York, NY
Y2  - 2023/01/28
UR  - accessmedicine.mhmedical.com/content.aspx?aid=1177463038
ER  -