TY  - CHAP
M1  - Book, Section
TI  - Peptic Ulcer and Related Disorders
A1  - Jameson, J. Larry
A1  - Fauci, Anthony S.
A1  - Kasper, Dennis L.
A1  - Hauser, Stephen L.
A1  - Longo, Dan L.
A1  - Loscalzo, Joseph
PY  - 2020
T2  - Harrison's Manual of Medicine, 20e
AB  - Peptic  ulcer  disease  (PUD)  occurs  most  commonly  in  duodenal  bulb  (duodenal  ulcer,  DU)  and  stomach  (gastric  ulcer,  GU).  It  may  also  occur  in  esophagus,  pyloric  channel,  duodenal  loop,  jejunum,  and  Meckel’s  diverticulum.  PUD  results  when  “aggressive”  factors  (gastric  acid,  pepsin)  overwhelm  “defensive”  factors  involved  in  mucosal  resistance  (gastric  mucus,  bicarbonate,  microcirculation,  prostaglandins,  mucosal  “barrier”)  and  from  effects  of  Helicobacter  pylori.  
SN  - 
PB  - McGraw-Hill Education
CY  - New York, NY
Y2  - 2024/04/19
UR  - accessmedicine.mhmedical.com/content.aspx?aid=1167067707
ER  -