TY - CHAP M1 - Book, Section TI - Arsenic Posisoning A1 - Smollin, Craig A1 - Olson, Kent R. A2 - Papadakis, Maxine A. A2 - McPhee, Stephen J. A2 - Rabow, Michael W. PY - 2020 T2 - Current Medical Diagnosis and Treatment 2020 AB - Arsenic is found in some pesticides and industrial chemicals and is used as a chemotherapeutic agent. Chronic arsenic poisoning has been associated with contaminated aquifers used for drinking water. Symptoms of acute poisoning usually appear within 1 hour after ingestion but may be delayed as long as 12 hours. They include abdominal pain, vomiting, watery diarrhea, and skeletal muscle cramps. Profound dehydration and shock may occur. In chronic poisoning, symptoms can be vague but often include pancytopenia, painful peripheral sensory neuropathy, and skin changes including melanosis, keratosis, and desquamating rash. Cancers of the lung, bladder, and skin have been reported. Urinary arsenic levels may be falsely elevated after certain meals (eg, seafood) that contain large quantities of a nontoxic form of organic arsenic. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2022/05/29 UR - accessmedicine.mhmedical.com/content.aspx?aid=1166176353 ER -