TY - CHAP M1 - Book, Section TI - Acute Hepatitis C & Other Causes of Acute Viral Hepatitis A1 - Friedman, Lawrence S. A2 - Papadakis, Maxine A. A2 - McPhee, Stephen J. A2 - Rabow, Michael W. PY - 2020 T2 - Current Medical Diagnosis and Treatment 2020 AB - Viruses other than HAV and HBV that can cause hepatitis are hepatitis C virus (HCV), hepatitis D virus (HDV) (delta agent), and hepatitis E virus (HEV) (an enterically transmitted hepatitis seen in epidemic form in Asia, the Middle East, and North Africa and sporadically in Western countries). Human pegivirus (formerly hepatitis G virus [HGV]) rarely, if ever, causes frank hepatitis. A related virus has been named human hepegivirus-1. A DNA virus designated the TT virus (TTV) has been identified in up to 7.5% of blood donors and found to be transmitted readily by blood transfusions, but an association between this virus and liver disease has not been established. A related virus known as SEN-V has been found in 2% of US blood donors, is transmitted by transfusion, and may account for some cases of transfusion-associated non-ABCDE hepatitis. In immunocompromised and rare immunocompetent persons, cytomegalovirus, Epstein-Barr virus, and herpes simplex virus should be considered in the differential diagnosis of hepatitis. Middle East respiratory syndrome (MERS), severe acute respiratory syndrome (SARS), Ebola virus infection, and influenza may be associated with marked serum aminotransferase elevations. Unidentified pathogens account for a small percentage of cases of acute viral hepatitis. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2022/05/25 UR - accessmedicine.mhmedical.com/content.aspx?aid=1166166921 ER -