TY - CHAP M1 - Book, Section TI - Antifungals A1 - Ghannoum, Mahmoud A1 - Salem, Iman A1 - Christensen, Luisa A2 - Kang, Sewon A2 - Amagai, Masayuki A2 - Bruckner, Anna L. A2 - Enk, Alexander H. A2 - Margolis, David J. A2 - McMichael, Amy J. A2 - Orringer, Jeffrey S. PY - 2019 T2 - Fitzpatrick's Dermatology, 9e AB - AT-A-GLANCETopical agents should be used for superficial fungal infections of limited extent.Topical agents have the advantage of low cost, nonprescription availability, ease of use, and high patient compliance.Topical antifungals include imidazoles, allylamines, benzylamines, polyenes, and ciclopirox.A number of new carrier vehicles have been investigated to improve the bioavaliabilty of topical antifungals.Systemic agents should be used to treat onychomycosis and tinea capitis, or when superficial fungal infection affects a large surface area.Attention should be paid to drug–drug interactions when prescribing systemic antifungals.Combination therapy with topical and systemic drugs presents several advantages. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/10/07 UR - accessmedicine.mhmedical.com/content.aspx?aid=1161343881 ER -