TY - CHAP M1 - Book, Section TI - Raynaud Phenomenon A1 - Kurtzman, Drew A1 - Vleugels, Ruth Ann A2 - Kang, Sewon A2 - Amagai, Masayuki A2 - Bruckner, Anna L. A2 - Enk, Alexander H. A2 - Margolis, David J. A2 - McMichael, Amy J. A2 - Orringer, Jeffrey S. PY - 2019 T2 - Fitzpatrick's Dermatology, 9e AB - AT-A-GLANCERaynaud phenomenon is a vascular disorder characterized by recurrent episodic attacks of digital ischemia provoked by exposure to cold or emotional stress.Affects up to 10% of the population, 4:1 female-to-male ratio.Classified as primary (idiopathic) and secondary (underlying disease or cause present) forms; severity ranges from mild/benign to severe with loss of tissue and risk of amputation.Connective tissue diseases, particularly systemic sclerosis, are among the most common underlying causes of secondary Raynaud phenomenon.Behavioral modification, pharmacologic therapies, and surgical interventions are effective at reducing the frequency and severity of attacks. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/04/20 UR - accessmedicine.mhmedical.com/content.aspx?aid=1161350381 ER -