TY - CHAP M1 - Book, Section TI - Relapsing Polychondritis A1 - Francès, Camille A2 - Kang, Sewon A2 - Amagai, Masayuki A2 - Bruckner, Anna L. A2 - Enk, Alexander H. A2 - Margolis, David J. A2 - McMichael, Amy J. A2 - Orringer, Jeffrey S. PY - 2019 T2 - Fitzpatrick's Dermatology, 9e AB - AT-A-GLANCERelapsing polychondritis is a rare multisystem autoimmune disease.Different factors are implicated in the pathogenesis, including a genetic susceptibility, immunization against cartilaginous structures, and modification of cytokine and chemokine signatures.More than 30% of patients have an associated disease, mainly of autoimmune or hematologic origin.Recurrent episodes of chondritis lead to progressive destruction of cartilaginous structures.Other proteoglycan-rich structures, such as eyes, blood vessels, or inner ear, are also affected.Dermatologic manifestations occur frequently, especially in association with myelodysplasia. They are nonspecific and resemble those observed in Behçet disease and inflammatory bowel diseases. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/28 UR - accessmedicine.mhmedical.com/content.aspx?aid=1161333220 ER -