TY - CHAP M1 - Book, Section TI - Erythema Multiforme A1 - Roujeau, Jean-Claude A1 - Mockenhaupt, Maja A2 - Kang, Sewon A2 - Amagai, Masayuki A2 - Bruckner, Anna L. A2 - Enk, Alexander H. A2 - Margolis, David J. A2 - McMichael, Amy J. A2 - Orringer, Jeffrey S. PY - 2019 T2 - Fitzpatrick's Dermatology, 9e AB - AT-A-GLANCEErythema multiforme is a rare cutaneous or mucocutaneous eruption characterized by “target” lesions, predominantly on the face and extremities.The highest incidence was found in male children and young adults.It has a benign course but frequent recurrences, possible ocular complications.Most cases are related to infections (herpes simplex virus [HSV] and Mycoplasma pneumoniae). Medications are not a common cause, in contrast to the spectrum of drug-induced epidermal necrolysis (see Chap. 44) that are different diseases.Herpes-induced recurrences can be prevented by long-term use of anti-HSV medications. Thalidomide, mycophenolate mofetil, or both may be considered in recalcitrant, recurrent cases. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/28 UR - accessmedicine.mhmedical.com/content.aspx?aid=1161330067 ER -