TY - CHAP M1 - Book, Section TI - Transport & Metabolic Functions of the Liver A1 - Barrett, Kim E. A1 - Barman, Susan M. A1 - Brooks, Heddwen L. A1 - Yuan, Jason X.-J. PY - 2019 T2 - Ganong's Review of Medical Physiology, 26e AB - OBJECTIVESAfter studying this chapter, you should be able to:Understand the functional anatomy of the liver and the relative arrangements of hepatocytes, cholangiocytes, endothelial cells, and Kupffer cells.Define the characteristics of the hepatic circulation and its role in subserving the liver’s functions.Describe the major functions of the liver with respect to metabolism, detoxification, and excretion of hydrophobic substances.Identify the plasma proteins that are synthesized by the liver.Outline the mechanisms by which the liver contributes to whole body ammonia homeostasis and the consequences of the failure of these mechanisms, particularly for brain function.Describe the constituents of bile, its formation, and its role in the excretion of cholesterol and bilirubin.Identify the mechanisms that permit normal functioning of the gallbladder and the basis of gallstone disease. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/04/18 UR - accessmedicine.mhmedical.com/content.aspx?aid=1159054220 ER -