TY - CHAP M1 - Book, Section TI - Breast Cancer A1 - Hayes, Daniel F. A1 - Lippman, Marc E. A2 - Jameson, J. Larry A2 - Fauci, Anthony S. A2 - Kasper, Dennis L. A2 - Hauser, Stephen L. A2 - Longo, Dan L. A2 - Loscalzo, Joseph PY - 2018 T2 - Harrison's Principles of Internal Medicine, 20e AB - Breast cancer is a malignant proliferation of epithelial cells lining the ducts or lobules of the breast. In the year 2017, ~247,000 cases of invasive and 61,000 cases of in situ breast cancer and 41,000 deaths will occur in the United States. In addition, ~2000 men will be diagnosed with breast cancer. Epithelial malignancies of the breast are the most common cause of cancer in women (excluding skin cancer), accounting for about one-third of all cancer in women. As a result of improved treatment and earlier detection, the mortality rate from breast cancer has begun to decrease very substantially in the United States. This chapter does not consider rare malignancies presenting in the breast, such as sarcomas and lymphomas, but focuses on the epithelial cancers. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/10/05 UR - accessmedicine.mhmedical.com/content.aspx?aid=1160011626 ER -